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Descripción
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This database includes the results of the optimal parameters of multiple reaction mode for the analysis of six opium alkaloids and two internal standards by HPLC-MS/MS, the matrix-matched calibration curves corrected with isotope-labelled IS employed to quantification of OAs in ground poppy seeds, compilation of all results obtained in each of the grinding studies which is possible to evaluate the grinding time and compilation of all results obtained in each of the grinding studies which is possible to evaluate the consecutive grindings. (2024-04)
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Publicación relacionada
| Gema Casado-Hidalgo, Sonia Morante-Zarcero, Damián Pérez-Quintanilla, Isabel Sierra, Investigating the effect of different grinding conditions and methods on the concentration of opium alkaloids in poppy seeds as a good reduction practice, Journal of Food Composition and Analysis, Volume 129, 2024, 106098, ISSN 0889-1575, https://doi.org/10.1016/j.jfca.2024.106098
doi: https://doi.org/10.1016/j.jfca.2024.106098 |
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Notas
| Description of the project In recent years, following intoxications and false positive drug tests for poppy seeds, dangerously high concentrations of opium alkaloids (OAs) have been found. For this reason, health authorities are demanding studies to establish effective practices to reduce OAs in these seeds. Grinding, a common culinary process for various recipes, has previously been associated with potential morphine degradation. However, these studies have not established effective grinding conditions to decrease the concentration of all main OAs. Furthermore, due to the large variation in OAs concentration that can occur even in the same bag, this can be a difficult task. In view of the above, this study aimed to evaluate for the first time the impact of different grinding types, varying grinding time or repetitions, to determine any degradation trends of the main OAs present in poppy seeds. As a result, it was obtained a notable 20% degradation of morphine in the second grinding with grinders where the oil content of the seeds is not released, hinting at oil’s protective role against morphine oxidation. Therefore, the choice of grinding method is crucial. However, while acknowledging this, relying solely on this method as a good practice for OAs reduction may be insufficient, as it seems to have minimal impact on other OAs with any of the tested methods and conditions. |
