|
ID persistente
|
doi:10.21950/OCCIBS |
|
Fecha de publicación
|
2026-02-24 |
|
Título
| Proteomics and RNA-seq datasets associated with: “Tamoxifen mechanically reprograms the tumor microenvironment via HIF-1A and reduces cancer cell survival” |
|
Autor
| Del Rio Hernandez, Armandohttps://ror.org/03ths8210ORCIDhttps://orcid.org/0000-0001-5062-8910
Cortes Lopez, Jose Ernestohttps://ror.org/041kmwe10ORCIDhttps://orcid.org/0000-0001-6106-1323
Lachowski, Dariuszhttps://ror.org/041kmwe10ORCIDhttps://orcid.org/0000-0003-1194-8019
Robinson, Benjaminhttps://ror.org/041kmwe10ORCIDhttps://orcid.org/0000-0003-3968-6583
Sarper, Mugehttps://ror.org/041kmwe10ORCIDhttps://orcid.org/0000-0003-3864-6651
Teppo, Jaakko Sakarihttps://ror.org/040af2s02ORCIDhttps://orcid.org/0000-0003-1022-5572
Thorpe, Stephenhttps://ror.org/026zzn846ORCIDhttps://orcid.org/0000-0002-4707-7756
Lieberthal, Tylerhttps://ror.org/041kmwe10ORCIDhttps://orcid.org/0000-0002-3250-8162
Iwamoto, Kazunarihttps://ror.org/035t8zc32ORCIDhttps://orcid.org/0000-0001-9794-9420
Lee, Davidhttps://ror.org/026zzn846ORCIDhttps://orcid.org/0000-0001-7646-4643
Okada-Hatakeyama, Marikohttps://ror.org/035t8zc32
Varjosalo, Markkuhttps://ror.org/040af2s02ORCIDhttps://orcid.org/0000-0002-1340-9732 |
|
Contacto
|
Utilice el botón de e-mail de arriba para contactar.
Río Hernández, Armando del (Universidad Carlos III de Madrid) |
|
Descripción
| The project investigates how tamoxifen modulates the tumor microenvironment through mechanobiological changes involving HIF-1A, and how these changes influence cancer cell survival. The study integrates proteomics and RNA sequencing (RNA-seq) as described in the associated publication.
Proteomics analysis data deposited in PeptideAtlas under reference PASS01070. PSCs RNA sequencing (RNA-seq) data deposited in the European Nucleotide Archive (ENA) under accession ERP023834. This e-cienciaDatos entry is intended to provide institutional Open Access traceability by referencing the original repositories. |
|
Materia
| Ciencias médicas, de la salud y de la vida |
|
Palabra clave
| tamoxifen
mechanobiology
tumor microenvironment
HIF-1A
cancer cell survival
proteomics
mass spectrometry
RNA-seq
PSCs
EMBO Reports |
|
Publicación relacionada
| IsSupplementTo: Cortes, E., Lachowski, D., Robinson, B., Sarper, M., Teppo, J. S., Thorpe, S. D., Lieberthal, T. J., Iwamoto, K., Lee, D. A., Okada-Hatakeyama, M., Varjosalo, M. T., & Del Río Hernández, A. E. (2019). Tamoxifen mechanically reprograms the tumor microenvironment via HIF-1A and reduces cancer cell survival. EMBO Reports, 20(1), e46557. https://doi.org/10.15252/embr.201846557 handle 10016/49311 https://hdl.handle.net/10016/49311 |
|
Notas
| Data availability statements and identifiers are provided in the associated publication. Some PeptideAtlas datasets may require file transfer access (e.g., FTP or repository-specific download methods). For time-sensitive administrative needs, a minimal e-cienciaDatos record can be created to mint a DOI while full metadata and file handling are completed subsequently. |
|
Idioma
| Inglés |
|
Información de la subvención
| European Research Council: ERC 282901 (ForceRegulation)
Biotechnology and Biological Sciences Research Council: BB/N018532/1
Osaka University: ICR2-17-01
JSPS KAKENHI: 15KT0084 |
|
Depositante
| Río Hernández, Armando del |
|
Fecha de depósito
| 2026-02-16 |
|
Dataset relacionado
| PeptideAtlas: PASS01070 (proteomics dataset); European Nucleotide Archive (ENA): ERP023834 (PSCs RNA-seq dataset) |